Anti-FKBP12 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Peptidyl-prolyl cis-trans isomerase FKBP1A;PPIase FKBP1A;5.2.1.8;12 kDa FK506-binding protein;12 kDa FKBP;FKBP-12;Calstabin-1;FK506-binding protein 1A;FKBP-1A;Immunophilin FKBP12;Rotamase;FKBP1A;FKBP1, FKBP12;

Gene Name

Peptidyl-prolyl cis-trans isomerase FKBP1A

UniProt

P62942

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human FKBP12

Clonality

Monoclonal

Clone

Clone: AAFH-6

Tissue Specificity

Specifically expressed in stromal cells of breast carcinomas.

Applications

WB,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. .