Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody catalog # M04191. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein argonaute-3 ;Argonaute3 ;hAgo3;Argonaute RISC catalytic component 3;Eukaryotic translation initiation factor 2C 3 ;eIF-2C 3 ;eIF2C 3 ;AGO3;EIF2C3;

Gene Name

Protein argonaute-3

UniProt

Q9H9G7

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human EIF2C3

Clonality

Monoclonal

Clone

Clone: GGF-1

Tissue Specificity

Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. .