Anti-L1CAM Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-L1CAM Rabbit Monoclonal Antibody catalog # M00729. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Neural cell adhesion molecule L1;N-CAM-L1;NCAM-L1;CD171;L1CAM;CAML1, MIC5;

Gene Name

Neural cell adhesion molecule L1

UniProt

P32004

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human L1CAM

Clonality

Monoclonal

Clone

Clone: AAFD-12

Tissue Specificity

Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

140003 MW

Observed Molecular Weight

90 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell projection, growth cone . Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons. .