Anti-S100P Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-S100P Rabbit Monoclonal Antibody catalog # M01963. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Protein S100-P;Migration-inducing gene 9 protein;MIG9;Protein S100-E;S100 calcium-binding protein P;S100P;S100E;

Gene Name

Protein S100-P

UniProt

P25815

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human S100P

Clonality

Monoclonal

Clone

Clone: AOCH-19

Tissue Specificity

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up- regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. .

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and inly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

10400 MW

Observed Molecular Weight

33 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50

Subcellular Location

Nucleus. Cytoplasm. Cell projection, microvillus membrane. Colocalizes with S100PBP in the nucleus. Colocolizes with EZR in the microvilli in a calcium- dependent manner.