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Anti-SUZ12 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-SUZ12 Rabbit Monoclonal Antibody catalog # M00583. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Polycomb protein SUZ12;Chromatin precipitated E2F target 9 protein;ChET 9 protein;Joined to JAZF1 protein;Suppressor of zeste 12 protein homolog;SUZ12;CHET9, JJAZ1, KIAA0160;

Gene Name

Polycomb protein SUZ12

UniProt

Q15022

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human SUZ12

Clonality

Monoclonal

Clone

Clone: IEB-19

Tissue Specificity

Overexpressed in breast and colon cancer. .

Applications

WB,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

83055 MW

Observed Molecular Weight

47 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>ICC/IF 1:50-1:200<br>IP 1:50

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

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