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(Pyr5, N-Me-Phe8, Sar9) -Substance P (5-11)

(Pyr5, N-Me-Phe8, Sar9) -Substance P (5-11) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. (Pyr5, N-Me-Phe8, Sar9) -Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. (Pyr5, N-Me-Phe8, Sar9) -Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.

Product Specifications

Purity

≥95%

Molecular Weight

880.06

Notes

For research use only.

AA Sequence

{Pyr}-QF (-Me) F-Sar-LM-NH2

Available Sizes

Frequently Asked Questions

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