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Anti-MEKK2 MAP3K2 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-MEKK2 MAP3K2 Rabbit Monoclonal Antibody catalog # M02354. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mitogen-activated protein kinase kinase kinase 2;2.7.11.25;MAPK/ERK kinase kinase 2;MEK kinase 2;MEKK 2;MAP3K2;MAPKKK2, MEKK2;

Gene Name

Mitogen-activated protein kinase kinase kinase 2

UniProt

Q9Y2U5

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human MEKK2

Clonality

Monoclonal

Clone

Clone: FHC-13

Tissue Specificity

Highly expressed in the thymus and low in lymph nodes and spleen. .

Applications

WB,IHC,ICC,IF,IP,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

69741 MW

Observed Molecular Weight

100 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:5000-1:20000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:30<br>FC 1:50

Subcellular Location

Cytoplasm . Nucleus . Upon EGF stimulation, translocates into the nucleus.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

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