Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody catalog # M01605. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

C-C motif chemokine 19;Beta-chemokine exodus-3;CK beta-11;Epstein-Barr virus-induced molecule 1 ligand chemokine;EBI1 ligand chemokine;ELC;Macrophage inflammatory protein 3 beta;MIP-3-beta;Small-inducible cytokine A19;CCL19;ELC, MIP3B, SCYA19;

Gene Name

C-C motif chemokine 19

UniProt

Q99731

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CCL19

Clonality

Monoclonal

Clone

Clone: AHD-3

Tissue Specificity

Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. .