Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody catalog # M03483. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Kinesin-like protein KIF23;Kinesin-like protein 5;Mitotic kinesin-like protein 1;KIF23;KNSL5, MKLP1;

Gene Name

Kinesin-like protein KIF23

UniProt

Q02241

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human MKLP1

Clonality

Monoclonal

Clone

Clone: EG-11

Tissue Specificity

Expressed in the normal brain and also in malignant gliomas (at protein level). .

Applications

WB,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-ed motor enzyme that moves antiparallel microtubules in vitro. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

110059 MW

Observed Molecular Weight

106 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>ICC/IF 1:50-1:200

Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.

Protein Name

T-cell surface glycoprotein CD3 zeta chain