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Anti-CHD4 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-CHD4 Rabbit Monoclonal Antibody catalog # M01125. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Chromodomain-helicase-DNA-binding protein 4;CHD-4;3.6.4.12;ATP-dependent helicase CHD4;Mi-2 autoantigen 218 kDa protein;Mi2-beta;CHD4;

Gene Name

Chromodomain-helicase-DNA-binding protein 4

UniProt

Q14839

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CHD4

Clonality

Monoclonal

Clone

Clone: ABEI-3

Tissue Specificity

Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas. .

Applications

WB,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

218005 MW

Observed Molecular Weight

80 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>ICC/IF 1:50-1:200<br>FC 1:50

Subcellular Location

Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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