Anti-CD18 ITGB2 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-CD18 ITGB2 Rabbit Monoclonal Antibody catalog # M00458. Tested in WB, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrin beta-2;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;Complement receptor C3 subunit beta;CD18;ITGB2;CD18, MFI7;

Gene Name

Integrin beta-2

UniProt

P05107

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD18

Clonality

Monoclonal

Clone

Clone: AAIH-9

Tissue Specificity

Highly expressed in placenta. Low expression in small intestine, liver and colon. .

Applications

WB,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. .