Anti-NUMB Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-NUMB Rabbit Monoclonal Antibody catalog # M01206. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein numb homolog;h-Numb;Protein S171;NUMB;

Gene Name

Protein numb homolog

UniProt

P49757

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human NUMB

Clonality

Monoclonal

Clone

Clone: AOGI-14

Tissue Specificity

Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.