Anti-Bmi1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Bmi1 Rabbit Monoclonal Antibody catalog # M00313. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Polycomb complex protein BMI-1;Polycomb group RING finger protein 4;RING finger protein 51;BMI1;PCGF4, RNF51;

Gene Name

Polycomb complex protein BMI-1

UniProt

P35226

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human Bmi1

Clonality

Monoclonal

Clone

Clone: IHE-2

Tissue Specificity

Ubiquitously expressed in various human primary cells and tumor cell lines. .

Applications

WB,IHC,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. .