Anti-ATF1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-ATF1 Rabbit Monoclonal Antibody catalog # M01600. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Cyclic AMP-dependent transcription factor ATF-1;cAMP-dependent transcription factor ATF-1;Activating transcription factor 1;Protein TREB36;ATF1;

Gene Name

Cyclic AMP-dependent transcription factor ATF-1

UniProt

P18846

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ATF1

Clonality

Monoclonal

Clone

Clone: HBF-1

Tissue Specificity

Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597). Expressed in melanocytes (PubMed:23999003). .

Applications

WB,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. .