Anti-IRF2 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-IRF2 Rabbit Monoclonal Antibody catalog # M02935. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Interferon regulatory factor 2;IRF-2;IRF2;

Gene Name

Interferon regulatory factor 2

UniProt

P14316

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human IRF2

Clonality

Monoclonal

Clone

Clone: HAC-9

Tissue Specificity

Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .

Applications

WB,IHC,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. .