Anti-CD68/Sr D1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-CD68/Sr D1 Rabbit Monoclonal Antibody catalog # M00602-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Macrosialin;Gp110;CD68;CD68;

Gene Name

Macrosialin

UniProt

P34810

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human CD68

Clonality

Monoclonal

Clone

Clone: GBE-3

Tissue Specificity

Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37408 MW

Observed Molecular Weight

32-42 kDa, 65 kDa, 75 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:1000

Subcellular Location

Isoform Short: Cell membrane; Single-pass type I membrane protein.

Protein Name

T-cell surface glycoprotein CD4

Curated Selection

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