Anti-SHP2 PTPN11 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-SHP2 PTPN11 Rabbit Monoclonal Antibody catalog # M00150-1. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tyrosine-protein phosphatase non-receptor type 11;3.1.3.48;Protein-tyrosine phosphatase 1D;PTP-1D;Protein-tyrosine phosphatase 2C;PTP-2C;SH-PTP2;SHP-2;Shp2;SH-PTP3;PTPN11;PTP2C, SHPTP2;

Gene Name

Tyrosine-protein phosphatase non-receptor type 11

UniProt

Q06124

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human SHP2

Clonality

Monoclonal

Clone

Clone: GBO-16

Tissue Specificity

Widely expressed, with highest levels in heart, brain, and skeletal muscle. .

Applications

WB,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. .