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Anti-DKK1 Rabbit Monoclonal Antibody, Carrier-free

Selected Variant

M00632-carrier-free

Size: 100 µL

Boster Bio Anti-DKK1 Rabbit Monoclonal Antibody catalog # M00632. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Dickkopf-related protein 1;Dickkopf-1;Dkk-1;hDkk-1;SK;DKK1;UNQ492/PRO1008;

Gene Name

Dickkopf-related protein 1

UniProt

O94907

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human DKK1

Clonality

Monoclonal

Clone

Clone: FHG-4

Tissue Specificity

Placenta.

Applications

WB,IHC,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28672 MW

Observed Molecular Weight

26 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Subcellular Location

Secreted.

Protein Name

T-cell surface glycoprotein CD4

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