Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody catalog # M01473. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Beta-adrenergic receptor kinase 1;Beta-ARK-1;2.7.11.15;G-protein coupled receptor kinase 2;ADRBK1;BARK, BARK1, GRK2;

Gene Name

Beta-adrenergic receptor kinase 1

UniProt

P25098

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human GRK2

Clonality

Monoclonal

Clone

Clone: EGE-1

Tissue Specificity

Expressed in peripheral blood leukocytes. .

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. .