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Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody catalog # M00078. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Nuclear factor erythroid 2-related factor 2;NF-E2-related factor 2;NFE2-related factor 2;HEBP1;Nuclear factor, erythroid derived 2, like 2;NFE2L2;NRF2;

Gene Name

Nuclear factor erythroid 2-related factor 2

UniProt

Q16236

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human Nrf2

Clonality

Monoclonal

Clone

Clone: AGH-14

Tissue Specificity

Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

67827 MW

Observed Molecular Weight

70 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:100-1:500<br>IP 1:50

Subcellular Location

Cytoplasm, cytosol. Nucleus. Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.

Protein Name

P2X purinoceptor 1

Curated Selection

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