Anti-AhR Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-AhR Rabbit Monoclonal Antibody catalog # M00225. Tested in WB, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Aryl hydrocarbon receptor;Ah receptor;AhR;Class E basic helix-loop-helix protein 76;bHLHe76;AHR;BHLHE76;

Gene Name

Aryl hydrocarbon receptor

UniProt

P35869

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human AhR

Clonality

Monoclonal

Clone

Clone: AOHI-1

Tissue Specificity

Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. .

Applications

WB,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. .