Anti-TBP/Tata Binding Protein Tbp Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-TBP/Tata Binding Protein Tbp Rabbit Monoclonal Antibody catalog # M00302. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

TATA-box-binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;Transcription initiation factor TFIID TBP subunit;TBP;GTF2D1, TF2D, TFIID;

Gene Name

TATA-box-binding protein

UniProt

P20226

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human TBP

Clonality

Monoclonal

Clone

Clone: DOA-20

Tissue Specificity

Widely expressed, with levels highest in the testis and ovary. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. .