Anti-Phospho-Glycogen synthase 1 (S641) GYS1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Phospho-Glycogen synthase 1 (S641) GYS1 Rabbit Monoclonal Antibody catalog # P03512-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Product Specifications

Phospho Site

S641

Synonyms

Glycogen [starch] synthase, muscle;2.4.1.11;GYS1;GYS;

Gene Name

Glycogen [starch] synthase, muscle

UniProt

P13807

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human Phospho-Glycogen synthase 1 (S641)

Clonality

Monoclonal

Clone

Clone: DCH-7

Tissue Specificity

Specifically expressed in immune and hematopoietic cells. Expressed in bone marrow and blood cells. Levels vary considerably within this compartment. Present in at least 74% of immature CD34+ cells, whereas within the more mature population of CD33+ cells, it is present in only 10% of cells. Present in the majority of T-cells, while it is present in a minority of B-cells (at protein level). .

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

83786 MW

Observed Molecular Weight

40 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50

Subcellular Location

Cytoplasm . Cell membrane ; Peripheral membrane protein . Membrane raft . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Translocates to the plasma membrane when activated, translocation is probably due to different mechanisms depending on the stimulus and cell type. Translocates from the cytoplasm to membrane ruffles in a FCGR3/CD16-dependent manner. Colocalizes with FC-gamma-RIIB receptor (FCGR2B) or FCGR3/CD16 at membrane ruffles. Tyrosine phosphorylation may also participate in membrane localization. .