Anti-Phospho-Histone H2A (S129) HIST1H2AB Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Phospho-Histone H2A (S129) HIST1H2AB Rabbit Monoclonal Antibody catalog # P30931. Tested in WB application. This antibody reacts with Yeast.

Product Specifications

Phospho Site

S129

Synonyms

Histone H2A.2;HTA2;H2A2;YBL003C;YBL0103;

Gene Name

Histone H2A.2

UniProt

P04912

Host

Rabbit

Reactivity

Yeast

Immunogen

A synthesized peptide derived from yeast Phospho-Histone H2A (S129)

Clonality

Monoclonal

Clone

Clone: DEE-8

Tissue Specificity

Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .