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Anti-MAP2 Antibody (Monoclonal, HM-2), Carrier-free

Boster Bio Anti-MAP2 Antibody (Monoclonal, HM-2) catalog # MA1057. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2 (MAP2)is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.

Synonyms

Microtubule-associated protein 2;MAP-2;Map2;Mtap2;

Gene Name

Microtubule-associated protein 2

Gene ID

Human(4133), Mouse(17756), Rat(25595)

UniProt

P15146

Host

Mouse

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Rat brain microtubule-associated proteins (MAPs).

Clonality

Monoclonal

Clone

Clone: HM-2

Applications

IHC,WB

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

References & Citations

1. MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2 (MAP2)is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

202411 MW

Observed Molecular Weight

42 kDa

Fragment

Mouse IgG1

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, mouse, rat, By Heat <br>Western blot, 0.5-2μg/ml, Human, mouse, rat<br>

Subcellular Location

Cytoplasm, cytoskeleton .

Sequence Similarities

Contains 3 Tau/MAP repeats.

Protein Name

Microtubule-associated protein 2

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