Anti-Biglycan/BGN Antibody Picoband®, Carrier-free

Boster Bio Anti-Biglycan/BGN Antibody Picoband® catalog # A02090-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.

Synonyms

BGN; SLRR1A; Biglycan; Bone/cartilage proteoglycan I; PG-S1

Gene Name

biglycan

Gene ID

633

UniProt

P21810

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Biglycan/BGN, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Applications

WB,IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Camera, G., Stella, G., Camera, A. New X linked spondyloepimetaphyseal dysplasia: report on eight affected males in the same family. J. Med. Genet. 31: 371-376, 1994. 2. Chatterjee, A., Faust, C. J., Herman, G. E. Genetic and physical mapping of the biglycan gene on the mouse X chromosome. Mammalian Genome 4: 33-36, 1993. 3. Cho, S. Y., Bae, J.-S., Kim, N. K. D., Forzano, F., Girisha, K. M., Baldo, C., Faravelli, F., Cho, T.-J., Kim, D., Lee, K. Y., Ikegawa, S., Shim, J. S., Ko, A.-R., Miyake, N., Nishimura, G., Superti-Furga, A., Spranger, J., Kim, O.-H., Park, W.-Y., Jin, D.-K. BGN mutations in X-linked spondyloepimetaphyseal dysplasia. Am. J. Hum. Genet. 98: 1243-1248, 2016.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.