Anti-beta-Actin ACTB Antibody Picoband® (HRP), Carrier-free

Boster Bio Anti-beta-Actin ACTB Antibody (HRP) (Catalog # A01263-HRP). Tested in WB applications. This antibody reacts with Human, Mouse, Rat, Monkey, Chicken, Zebrafish. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-Actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

Synonyms

HRP-Actin, Beta-Actin, Actin, Beta actin, b actin

Gene Name

Actin, beta

UniProt

P60709

Host

Rabbit

Reactivity

Chicken,Human,Monkey,Mouse,Rat,Zebrafish

Cross Reactivity

HRP-Beta-Actin antibody is human, mouse, rat, rabbit, chicken, and drosophila reactive.

Immunogen

HRP-Beta-Actin antibody was raised against a synthetic peptide containing 16 amino acids near the amino terminus of beta-actin.

Clonality

Polyclonal

Label

HRP

Tissue Specificity

Widely expressed, with the highest expression in lung, spleen and thymus.

Applications

Purification

HRP-Beta-Actin antibody is affinity chromatography purified via peptide column.

Concentration

0.5 mg/mL

Form

Liquid

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:29581253). Actin exists in both monomeric (G- actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947).