C5a Inhibitory Sequence
The C5a-related octapeptide Phe-Lys-Ala-Cha-Cha-Leu-D-Ala-Arg possesses a high binding affinity for polymorphonuclear leukocyte membranes (Ki = 0.09 μM) . It has therefore been used as a leading analog for the development of specific C5a antagonists, which are of considerable therapeutic interest for the treatment of inflammatory disorders and tissue damage.
Product Specifications
Purity
≥95%
Molecular Weight
1011.3
Notes
For research use only.
AA Sequence
FKA-{β-cyclohexyl-Ala-β-cyclohexyl-Ala}-L{D-Ala}-R
Available Sizes
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