Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ABCE1 Antibody Picoband® (iFluor647 Conjugate)

Boster Bio Anti-ABCE1 Antibody Picoband® catalog # PB10020. Tested in Flow Cytometry, IP, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

Synonyms

ATP-binding cassette sub-family E member 1;2'-5'-oligoadenylate-binding protein;HuHP68;RNase L inhibitor;Ribonuclease 4 inhibitor;RNS4I;ABCE1;RLI, RNASEL1, RNASELI, RNS4I;OK/SW-cl.40;

Gene Name

ATP-binding cassette sub-family E member 1

UniProt

P61221

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human ABCE1 recombinant protein (Position: K419-D599). Human ABCE1 shares 100% amino acid (aa) sequence identity with mouse ABCE1.

Clonality

Polyclonal

Tissue Specificity

Liver > pancreas > brain > kidney > heart > placenta.

Applications

Flow Cytometry,IP,IF,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB10020

Product MSDS

https://www.bosterbio.com/msds?sku=PB10020

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Immunoprecipitation, 0.5-2 μg/ml, Human<br> Flow Cytometry(Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br>

Subcellular Location

Cytoplasm . Mitochondrion . Localized to clusters of virus formation at the plasma membrane.

Sequence Similarities

Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Protein Name

ATP-binding cassette sub-family E member 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal Myosin heavy chain 11 Antibody (ID8) [PerCP]
NBP2-47899PCP 0.1 mL

Mouse Monoclonal Myosin heavy chain 11 Antibody (ID8) [PerCP]

Ask
View Details
Recombinant Human CD163 Fc Chimera Protein CF
11228-CD-050 50 µg

Recombinant Human CD163 Fc Chimera Protein CF

Ask
View Details
MRPS21P2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
30555111 3 x 1.0 µg

MRPS21P2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Ask
View Details
MIB1 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
28568124 3 x 1.0μg DNA

MIB1 CRISPRa sgRNA lentivector (set of three targets)(Mouse)

Ask
View Details
Rabbit Polyclonal Sodium Potassium ATPase Beta 1 Antibody
NBP2-54665-25ul 25 µL

Rabbit Polyclonal Sodium Potassium ATPase Beta 1 Antibody

Ask
View Details
Rabbit Polyclonal TRERF1 Antibody [PE]
NB100-81654PE 0.1 mL

Rabbit Polyclonal TRERF1 Antibody [PE]

Ask
View Details