Anti-LSM11 Antibody Picoband®, APC Conjugate

LSM11 is a component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing .Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cellcycle progression from G1 to S phases.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/15/2018. 2. Pillai, R. S., Grimmler, M., Meister, G., Will, C. L., Luhrmann, R., Fischer, U., Schumperli, D. Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev. 17: 2321-2333, 2003. 3. Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M.-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., Albawardi, W., Fremond, M.-L., and 44 others. cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing. Nature Genet. 52: 1364-1372, 2020.

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.