Anti-NRAP Antibody Picoband®, APC Conjugate

NRAP may be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix.

1. Luo, G., Leroy, E., Kozak, C. A., Polymeropoulos, M. H., Horowits, R. Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics 45: 229-232, 1997. 2. Luo, G., Zhang, J. Q., Nguyen, T.-P., Herrera, A. H., Paterson, B., Horowits, R. Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle. Cell Motil. Cytoskeleton 38: 75-90, 1997. 3. Truszkowska, G. T., Bilinska, Z. T., Muchowicz, A., Pollak, A., Biernacka, A., Kozar-Kaminska, K., Stawinski, P., Gasperowicz, P., Kosinska, J., Zielinski, T., Ploski, R. Homozygous truncating mutation in NRAP gene identified by whole exome sequencing in a patient with dilated cardiomyopathy. Sci. Rep. 7: 3362, 2017. Note: Electronic Article.

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.