Anti-TAS2R10 Antibody Picoband®, APC Conjugate

Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene. This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.

1. Adler, E., Hoon, M. A., Mueller, K. L., Chandrashekar, J., Ryba, N. J. P., Zuker, C. S. A novel family of mammalian taste receptors. Cell 100: 693-702, 2000. 2. Chandrashekar, J., Hoon, M. A., Ryba, N. J. P., Zuker, C. S. The receptors and cells for mammalian taste. Nature 444: 288-294, 2006. 3. Deshpande, D. A., Wang, W. C. H., McIlmoyle, E. L., Robinett, K. S., Schillinger, R. M., An, S. S., Sham, J. S. K., Liggett, S. B. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nature Med. 16: 1299-1304, 2010.

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5 μg/ml, Human<br> Immunofluorescence, 5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>