Anti-BPIFB1 Antibody Picoband®, APC Conjugate

BPI fold-containing family B member 1 (BPIFB1) is a protein that in humans is encoded by the BPIFB1 gene. The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.

E.coli-derived human BPIFB1 recombinant protein (Position: T26-K477). Human BPIFB1 shares 58.9% and 57.4% amino acid (aa) sequence identity with mouse and rat BPIFB1, respectively.

1. Wei, F., Tang, L., He, Y., Wu, Y., Shi, L., Xiong, F., ... & Zeng, Z. (2018). BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression. Cell Death & Disease, 9(4), 432. 2. Gao, J., Ohlmeier, S., Nieminen, P., Toljamo, T., Tiitinen, S., Kanerva, T., ... & Pulkkinen, V. (2015). Elevated sputum BPIFB1 levels in smokers with chronic obstructive pulmonary disease: a longitudinal study. American Journal of Physiology-Lung Cellular and Molecular Physiology, 309(1), L17-L26. 3. Yang, Y., Liao, Q., Wei, F., Li, X., Zhang, W., Fan, S., ... & Li, G. (2013). LPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathways. PloS one, 8(5), e62869.

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.