Anti-MMD Antibody Picoband®, APC Conjugate

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages.

E.coli-derived human MMD recombinant protein (Position: R20-A182). Human MMD shares 100% amino acid (aa) sequence identity with both mouse and rat MMD.

1. Rehli, M., Krause, S. W., Schwarzfischer, L., Kreutz, M., Andreesen, R. Molecular cloning of a novel macrophage maturation-associated transcript encoding a protein with several potential transmembrane domains. Biochem. Biophys. Res. Commun. 217: 661-667, 1995. 2. Tang, Y. T., Hu, T., Arterburn, M., Boyle, B., Bright, J. M., Emtage, P. C., Funk, W. D. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. J. Molec. Evol. 61: 372-380, 2005.

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.