Anti-NLRP9 Antibody Picoband®, APC Conjugate

Boster Bio Anti-NLRP9 Antibody Picoband® catalog # A14119-1. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.

Synonyms

RNA-binding protein 47;RNA-binding motif protein 47;RBM47;

Gene Name

RNA-binding protein 47

Gene ID

338321

UniProt

Q7RTR0

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NLRP9 recombinant protein (Position: H118-H746).

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Inohara, N., Nunez, G. NODs: intracellular proteins involved in inflammation and apoptosis. Nature Rev. Immun. 3: 371-382, 2003. 2. Tschopp, J., Martinon, F., Burns, K. NALPs: a novel protein family involved in inflammation. Nature Rev. Molec. Cell Biol. 4: 95-104, 2003. 3. Zhu, S., Ding, S., Wang, P., Wei, Z., Pan, W., Palm, N. W., Yang, Y., Yu, H., Li, H.-B., Wang, G., Lei, X., de Zoete, M. R., and 13 others. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature 546: 667-670, 2017.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.