Anti-RNF212 Antibody Picoband®, APC Conjugate

Boster Bio Anti-RNF212 Antibody Picoband® catalog # A11605-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.

Synonyms

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

Gene Name

eva-1 homolog A, regulator of programmed cell death

Gene ID

285498

UniProt

Q495C1

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RNF212 recombinant protein (Position: Q12-E271).

Clonality

Polyclonal

Tissue Specificity

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Ahuja, J. S., Sandhu, R., Mainpal, R., Lawson, C., Henley, H., Hunt, P. A., Yanowitz, J. L., Borner, G. V. Control of meiotic pairing and recombination by chromosomally tethered 26S proteasome. Science 355: 408-411, 2017. 2. Jantsch, V., Pasierbek, P., Mueller, M. M., Schweizer, D., Jantsch, M., Loidl, J. Targeted gene knockout reveals a role in meiotic recombination for ZHP-3, a Zip3-related protein in Caenorhabditis elegans. Molec. Cell. Biol. 24: 7998-8006, 2004. 3. Kong, A., Thorleifsson, G., Stefansson, H., Masson, G., Helgason, A., Gudbjartsson, D. F., Jonsdottir, G. M., Gudjonsson, S. A., Sverrisson, S., Thorlacius, T., Jonasdottir, A., Hardarson, G. A., Palsson, S. T., Frigge, M. L., Gulcher, J. R., Thorsteinsdottir, U., Stefansson, K. Sequence variants in the RNF212 gene associate with genome-wide recombination rate. Science 319: 1398-1401, 2008.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.