Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PON2 Antibody Picoband®, APC Conjugate

Boster Bio Anti-PON2 Antibody Picoband® catalog # A02027-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

PON2 is an enzyme that in humans is encoded by the PON2 gene. It is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.

Synonyms

Tripartite motif-containing protein 6; RING finger protein 89; RING-type E3 ubiquitin transferase TRIM6; TRIM6; RNF89

Gene Name

tripartite motif containing 6

Gene ID

5445

UniProt

Q15165

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PON2 recombinant protein (Position: D38-D337).

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas. .

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells. Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response .

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. "Entrez Gene: PON2 paraoxonase 2" 2. Mochizuki H, Scherer SW, Xi T, Nickle DC, Majer M, Huizenga JJ, Tsui LC, Prochazka M (Aug 1998). "Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence". Gene 213 (1–2): 149–57. 3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (Sep 1996). "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family". Genomics 33 (3): 498–507.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02027-2

Product MSDS

https://www.bosterbio.com/msds?sku=A02027-2

Calculated Molecular Weight

37492 MW

Observed Molecular Weight

39 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Cytoplasm.

Protein Name

Tripartite motif-containing protein 6

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LOC689618 CRISPRa sgRNA lentivector (set of three targets)(Rat)
27457126 3 x 1.0μg DNA

LOC689618 CRISPRa sgRNA lentivector (set of three targets)(Rat)

Ask
View Details
FOXN2 Polyclonal Antibody, PE-Cy5.5 Conjugated
bs-13205R-PE-Cy5.5 100 µL

FOXN2 Polyclonal Antibody, PE-Cy5.5 Conjugated

Ask
View Details
Human Serine/Threonine-Protein Kinase Lmtk3 (Lmtk3) Elisa Kit
EKC35512 96 Tests

Human Serine/Threonine-Protein Kinase Lmtk3 (Lmtk3) Elisa Kit

Ask
View Details
RAI2 Protein Vector (Rat) (pPM-C-HA)
38456026 500 ng

RAI2 Protein Vector (Rat) (pPM-C-HA)

Ask
View Details
TH1L Peptide - N-terminal region
MBS3238513-01 0.1 mg

TH1L Peptide - N-terminal region

Ask
View Details
TH1L Peptide - N-terminal region
MBS3238513-02 5x 0.1 mg

TH1L Peptide - N-terminal region

Ask
View Details