Anti-BAL/SLC27A5 Antibody Picoband®, APC Conjugate

Boster Bio Anti-BAL/SLC27A5 Antibody Picoband® catalog # A09287-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Bile acyl-CoA synthetase is an enzyme that in humans is encoded by the SLC27A5 gene. The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog.

Synonyms

A-kinase anchor protein 2;AKAP-2;AKAP-KL;Protein kinase A-anchoring protein 2;PRKA2;AKAP2;KIAA0920, PRKA2;

Gene Name

A-kinase anchor protein 2

Gene ID

10998

UniProt

Q9Y2P5

Host

Rabbit

Reactivity

Human,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human BAL/SLC27A5 recombinant protein (Position: I204-L690).

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). .

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Berger, J., Truppe, C., Neumann, H., Forss-Petter, S. A novel relative of the very-long-chain acyl-CoA synthetase and fatty acid transporter protein genes with a distinct expression pattern. Biochem. Biophys. Res. Commun. 247: 255-260, 1998. 2. Chong, C. P. K., Mills, P. B., McClean, P., Gissen, P., Bruce, C., Stahlschmidt, J., Knisely, A. S., Clayton, P. T. Bile acid-CoA ligase deficiency--a new inborn error of bile acid metabolism. J. Inherit. Metab. Dis. 35: 521-532, 2012. 3. Doege, H., Baillie, R. A., Ortegon, A. M., Tsang, B., Wu, Q., Punreddy, S., Hirsch, D., Watson, N., Gimeno, R. E., Stahl, A. Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic liver homeostasis. Gastroenterology 130: 1245-1258, 2006.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.