Anti-SGT2/SGTB Antibody Picoband®, APC Conjugate

Boster Bio Anti-SGT2/SGTB Antibody Picoband® catalog # A13056-1. Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Predicted to enable molecular adaptor activity. Predicted to be involved in positive regulation of chaperone-mediated protein folding; posttranslational protein targeting to endoplasmic reticulum membrane; and ubiquitin-dependent ERAD pathway. Predicted to be part of TRC complex. Predicted to be active in membrane.

Synonyms

Alpha-amylase 1;3.2.1.1;1,4-alpha-D-glucan glucanohydrolase 1;Salivary alpha-amylase;AMY1A;AMY1;AMY1B;AMY1;AMY1C;AMY1;

Gene Name

Alpha-amylase 1

Gene ID

54557

UniProt

Q96EQ0

Host

Rabbit

Reactivity

Human,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SGT2/SGTB recombinant protein (Position: Q20-A268).

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Qi, Tian, He-Fen, Sun, Wen-Jing, & Wang, et al. (2019). Mirrna-365b promotes hepatocellular carcinoma cell migration and invasion by downregulating sgtb. Future oncology (London, England). 2. Cao, M. , Xu, W. , Yu, J. , Zheng, H. , Tan, X. , & Li, L. , et al. (2013). Up-regulation of sgtb is associated with neuronal apoptosis after neuroinflammation induced by lipopolysaccharide. Journal of Molecular Histology, 44(5), 507-518. 3. Heavner, G. A. , Audhya, T. , & Goldstein, G. . (1990). Peptide analogs of thymopentin distinguish distinct thymopoietin receptor specificities on two human t cell lines. Regulatory Peptides, 27(2), 257-262.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.