Anti-TMEM97 Antibody Picoband®, APC Conjugate

Boster Bio Anti-TMEM97 Antibody Picoband® catalog # A08336-1. Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels .

Synonyms

Histone-lysine N-methyltransferase SETDB2; Chronic lymphocytic leukemia deletion region gene 8 protein; Lysine N-methyltransferase 1F; SET domain bifurcated 2; SETDB2; C13orf4; CLLD8; KMT1F

Gene Name

SET domain bifurcated histone lysine methyltransferase 2

Gene ID

27346

UniProt

Q5BJF2

Host

Rabbit

Reactivity

Human,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TMEM97 recombinant protein (Position: A5-L141).

Clonality

Polyclonal

Tissue Specificity

Highly expressed in reproductive organs, such as testis, ovary and prostate.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Bartz, F., Kern, L., Erz, D., Zhu, M., Gilbert, D., Meinhof, T., Wirkner, U., Erfle, H., Muckenthaler, M., Pepperkok, R., Runz, H. Identification of cholesterol-regulating genes by targeted RNAi screening. Cell Metab. 10: 63-75, 2009. 2. Kayed, H., Kleeff, J., Ding, J., Hammer, J., Giese, T., Zentgraf, H., Buchler, M. W., Friess, H. Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract. Histol. Histopath. 19: 1021-1031, 2004. 3. Malhotra, K., Luehrsen, K. R., Costello, L. L., Raich, T. J., Sim, K., Foltz, L., Davidson, S., Xu, H., Chen, A., Yamanishi, D. T., Lindemann, G. W., Cain, C. A., Madlansacay, M. R., Hashima, S. M., Pham, T. L., Mahoney, W., Schueler, P. A. Identification of differentially expressed mRNAs in human fetal liver across gestation. Nucleic Acids Res. 27: 839-847, 1999.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.