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Anti-IKB epsilon/Nfkbie Antibody Picoband®, APC Conjugate

Boster Bio Anti-IKB epsilon/Nfkbie Antibody Picoband® catalog # A07073-1. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene. Predicted to be involved in D-serine transport. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Predicted to be located in several cellular components, including Golgi apparatus; nuclear lumen; and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; eye; genitourinary system; and thymus. Orthologous to human NFKBIE (NFKB inhibitor epsilon).

Synonyms

Mimecan; Osteoglycin; Ogn; Og

Gene Name

osteoglycin

Gene ID

18037

UniProt

O54910

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse IKB epsilon/Nfkbie recombinant protein (Position: Q111-D364).

Clonality

Polyclonal

Tissue Specificity

Expressed in kidney.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Hoffmann, A., Levchenko, A., Scott, M. L., Baltimore, D. The I-kappa-B-NF-kappa-B signaling module: temporal control and selective gene activation. Science 298: 1241-1245, 2002. Note: Erratum: Science 318: 1550 only, 2007. 2. Li, Z., Nabel, G. J. A new member of the I-kappa-B protein family, I-kappa-B epsilon, inhibits RelA (p65)-mediated NF-kappa-B transcription. Molec. Cell. Biol. 17: 6184-6190, 1997. 3. Ting, A. Y., Endy, D. Decoding NF-kappa-B signaling. Science 298: 1189-1190, 2002.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

41 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml/ml, Mouse<br> ELISA, 0.1-0.5 μg/ml/ml, Mouse<br>

Subcellular Location

Secreted, extracellular space, extracellular matrix.

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