Anti-Slc7a9 Antibody Picoband®, APC Conjugate

Boster Bio Anti-Slc7a9 Antibody Picoband® catalog # A03445-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

b (0,+)-type amino acid transporter 1, also known as b (0,+)AT1, is a protein which in humans is encoded by the SLC7A9 gene. This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. Alternate transcript variants, which encode the same protein, have been found for this gene.

Synonyms

Pulmonary surfactant-associated protein B; SP-B; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant-associated proteolipid SPL (Phe); SFTPB; SFTP3

Gene Name

surfactant protein B

Gene ID

30962

UniProt

Q9QXA6

Host

Rabbit

Reactivity

Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Slc7a9 recombinant protein (Position: M1-E487).

Clonality

Polyclonal

Tissue Specificity

Found in the synovial fluid of patients with rheumatoid arthritis. .

Applications

ELISA,Flow Cytometry,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Components

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

References & Citations

1. Brodehl, J., Gellissen, K., Kowalewski, S. Isolierter Defekt der tubulaeren Cystin-Rueckresorption in einer Familie mit idiopathischem Hypoparathyroidismus. Klin. Wschr. 45: 38-40, 1967. 2. Colombo, R. Dating the origin of the V170M mutation causing non-type I cystinuria in Libyan Jews by linkage disequilibrium and physical mapping of the SLC7A9 gene. Genomics 69: 131-134, 2000. 3. Dello Strologo, L., Pras, E., Pontesilli, C., Beccia, E., Ricci-Barbini, V., de Sanctis, L., Ponzone, A., Gallucci, M., Bisceglia, L., Zelante, L., Jimenez-Vidal, M., Font, M., Zorzano, A., Rousaud, F., Nunes, V., Gasparini, P., Palacin, M., Rizzoni, G. Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: a need for a new classification. J. Am. Soc. Nephrol. 13: 2547-2553, 2002.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.