Anti-Pannexin 2/PANX2 Picoband® Antibody, APC Conjugate

Boster Bio Anti-Pannexin 2/PANX2 Picoband® Antibody catalog # A08860-1. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Pannexin 2 is a protein that in humans is encoded by the PANX2 gene. It is mapped to 22q13.33. The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Pannexin-2; PANX2

Gene Name

pannexin 2

Gene ID

56666

UniProt

Q96RD6

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Pannexin 2/PANX2 recombinant protein (Position: E19-F677).

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Structural component of the gap junctions and the hemichannels.

Components

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

References & Citations

1. Bruzzone, R., Hormuzdi, S. G., Barbe, M. T., Herb, A., Monyer, H. Pannexins, a family of gap junction proteins expressed in brain. Proc. Nat. Acad. Sci. 100: 13644-13649, 2003. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/23/2004.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.