Anti-C Reactive Protein/CRP Antibody Picoband®, APC Conjugate

Boster Bio Anti-C Reactive Protein/CRP Antibody Picoband® catalog # A00249-4. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver.

Synonyms

C-reactive protein; C-reactive protein (1-205); CRP; PTX1

Gene Name

C-reactive protein

Gene ID

1401

UniProt

P02741

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human C Reactive Protein, which shares 68.8% and 53.1% amino acid (aa) sequence identity with mouse and rat C Reactive Protein, respectively.

Clonality

Polyclonal

Tissue Specificity

Found in plasma.

Applications

IHC,WB

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Components

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

References & Citations

1. Kilpatrick, J. M.; Volanakis, J. E. : Molecular genetics, structure, and function of C-reactive protein. Immun. Res. 10: 43-53, 1991. 2. Kuta, A. E.; Baum, L. L. : C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes. J. Exp. Med. 164: 321-326, 1986. 3. Oliveira, E. B.; Gotshlich, E. C.; Liu, T. : Primary structure of human C-reactive protein. J. Biol. Chem. 254: 489-502, 1979.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.