Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MAP3K20 Antibody Picoband® (APC Conjugate)

Boster Bio Anti-MAP3K20 Antibody Picoband® catalog # A00902-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Sterile alpha motif and leucine zipper containing kinase AZK, also known as ZAK, is a human gene. This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Mitogen-activated protein kinase kinase kinase 20

Gene Name

mitogen-activated protein kinase kinase kinase 20

UniProt

Q9NYL2

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human MAP3K20 recombinant protein (Position: F276-E511).

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.

Applications

ELISA,WB

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381). Involved in limb development (PubMed:26755636).

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00902-1

Product MSDS

https://www.bosterbio.com/msds?sku=A00902-1

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml<br> ELISA, 0.1-0.5μg/ml<br>

Subcellular Location

Cytoplasm.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Clcn6 activation kit by CRISPRa
GA204928 1 Kit

Mouse Clcn6 activation kit by CRISPRa

Ask
View Details
AARD (NM_001025357) Human Recombinant Protein
PH36210M5 20 µg

AARD (NM_001025357) Human Recombinant Protein

Ask
View Details
Rabbit Polyclonal DPY19L3 Antibody
NBP1-86489-25ul 25 µL

Rabbit Polyclonal DPY19L3 Antibody

Ask
View Details
Squalene Epoxidase (SQLE) (NM_003129) Human Over-expression Lysate
LS006713 100 µg

Squalene Epoxidase (SQLE) (NM_003129) Human Over-expression Lysate

Ask
View Details
HSA fraction V, lyophilized
HSA.FV.0050 50 g

HSA fraction V, lyophilized

Ask
View Details