Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Prostate Specific Antigen/KLK3 Antibody Picoband® (APC Conjugate)

Boster Bio Anti-Prostate Specific Antigen/KLK3 Antibody Picoband® catalog # PB9259. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

Synonyms

Prostate-specific antigen;PSA;3.4.21.77;Gamma-seminoprotein;Seminin;Kallikrein-3;P-30 antigen;Semenogelase;KLK3;APS;

Gene Name

Prostate-specific antigen

UniProt

P07288

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB9259

Product MSDS

https://www.bosterbio.com/msds?sku=PB9259

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/ml, Human<br>

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein Name

Prostate-specific antigen

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Omadacycline Impurity 1
RM-O542001-01 10 mg

Omadacycline Impurity 1

Ask
View Details
Omadacycline Impurity 1
RM-O542001-02 25 mg

Omadacycline Impurity 1

Ask
View Details
Omadacycline Impurity 1
RM-O542001-03 50 mg

Omadacycline Impurity 1

Ask
View Details
Omadacycline Impurity 1
RM-O542001-04 100 mg

Omadacycline Impurity 1

Ask
View Details
Rat Monoclonal CD30 Ligand/TNFSF8 Antibody (RM153)
NBP3-11992-0.2mg 0.2 mg

Rat Monoclonal CD30 Ligand/TNFSF8 Antibody (RM153)

Ask
View Details
TIGAR Double Nickase Plasmid (h2)
sc-401390-NIC-2 20 µg

TIGAR Double Nickase Plasmid (h2)

Ask
View Details