Anti-Fruit fly Spire Antibody-FITC Conjugate

Boster Bio Anti-Spire Antibody catalog # DZ41407. This antibody reacts with Fruit fly.

Product Specifications

Gene Name

spir

UniProt

Q9U1K1

Host

Rabbit

Reactivity

Fruit fly

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.

Purification

Immunogen affinity purified.

Concentration

500 μg/ml

Form

Liquid

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.