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Anti-RASL12 Antibody Picoband®, FITC Conjugate

Selected Variant

A15197-1-FITC

Size: 100 µg/Vial

Boster Bio Anti-RASL12 Antibody Picoband® catalog # A15197-1. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.

Gene Name

RASL12

Gene ID

51285

UniProt

Q9NYN1

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human RASL12 recombinant protein (Position: K7-K261). Human RASL12 shares 93.3% amino acid (aa) sequence identity with mouse RASL12.

Clonality

Polyclonal

Applications

WB,ICC,IF,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Wistow, G., Bernstein, S. L., Ray, S., Wyatt, M. K., Behal, A., Touchman, J. W., ... & Peterson, K. (2002). Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. Mol Vis, 8(21), 185-195. 2. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., ... & Wrana, J. L. (2005). High-throughput mapping of a dynamic signaling network in mammalian cells. Science, 307(5715), 1621-1625. 3. Lipp, J. J., Marvin, M. C., Shokat, K. M., & Guthrie, C. (2015). SR protein kinases promote splicing of nonconsensus introns. Nature structural & molecular biology, 22(8), 611.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

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