Anti-NECAB2 Antibody Picoband®, FITC Conjugate

Boster Bio Anti-NECAB2 Antibody Picoband® catalog # A13886-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

N-terminal EF-hand calcium-binding protein 2 is a protein that in humans is encoded by the NECAB2 gene. The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5.

Synonyms

RNA-binding protein 47;RNA-binding motif protein 47;RBM47;

Gene Name

RNA-binding protein 47

Gene ID

54550

UniProt

Q7Z6G3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NECAB2 recombinant protein (Position: M1-E337).

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Bernier, G., Vukovich, W., Neidhardt, L., Herrmann, B. G., Gruss, P. Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium. Development 128: 3987-3994, 2001. 2. Canela, L., Lujan, R., Lluis, C., Burgueno, J., Mallol, J., Canela, E. I., Franco, R., Ciruela, F. The neuronal Ca(2+)-binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor. Molec. Cell Neurosci. 36: 1-12, 2007. 3. Zhang, M.-D., Barde, S., Szordorai, E., Josephson, A., Mitsios, N., Watanabe, M., Attems, J., Lubec, G., Kovacs, G. G., Uhlen, M., Mulder, J., Harkany, T., Hokfelt, T. Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord. Brain Struct. Funct. 221: 3803-3823, 2016. Note: Erratum: Brain Struct. Funct. 221: 3843, 2016.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

64099 MW

Observed Molecular Weight

43 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/ml, -

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

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