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Anti-Plasmolipin/PLLP Antibody Picoband®, FITC Conjugate

Boster Bio Anti-Plasmolipin/PLLP Antibody Picoband® catalog # A10793. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

PLLP (Plasmolipin, also known as PMLP; TM4SF11), located on 16q13, is a Protein Coding gene. The gene produces a 19987 Da protein composed of 182 amino acids. Plasmolipin (PLLP) is a novel protein identified in human corneal epithelium and has been demonstrated to have a key role in epithelial cell differentiation in other tissues. Plasmolipin is a hydrophobic plasma membrane proteolipid present in both the kidney and brain. The mouse plasmolipin gene has the common organization of the 4-transmembrane (4TM) gene group, with 4 exons and a large first intron.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

NOVA alternative splicing regulator 2

Gene ID

51090

UniProt

Q9Y342

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Plasmolipin/PLLP recombinant protein (Position: M1-A142).

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Fischer, I., Sapirstein, V. S. Molecular cloning of plasmolipin: characterization of a novel proteolipid restricted to brain and kidney. J. Biol. Chem. 269: 24912-24919, 1994. 2. Hamacher, M., Pippirs, U., Kohler, A., Muller, H. W., Bosse, F. Plasmolipin: genomic structure, chromosomal localization, protein expression pattern, and putative association with Bardet-Biedl syndrome. Mammalian Genome 12: 933-937, 2001.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

29370 MW

Observed Molecular Weight

26 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

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